The latest 2025 fantasy baseball rankings for mixed 5×5 leagues feature Aaron Judge as the leading player, with Shohei Ohtani and Bobby Witt Jr. competing closely for the rest of the season. Updated as of May 28, these rankings highlight important shifts in player values based on recent performances and injury statuses.
These rankings, which will be updated weekly on Mondays, exclude several players who have dropped out due to poor performance or injuries. Notable names removed from the top 300 include Joc Pederson, Porter Hodge, Ryan Pressly, Luke Jackson, Jorge Polanco, Zach Dezenzo, Yu Darvish, Christopher Morel, Jacob Misiorowski, Griffin Canning, Jack Leiter, and Willi Castro.
Recent Player Movements and Injury Updates
Devin Williams has shown signs of improvement recently, although his brief return to the closer role on Tuesday, in place of Luke Weaver, was uneven; he secured the save despite allowing two runs against the Angels. This performance somewhat negates the progress he appeared to have made in the previous scoreless outings.
A strong focus remains on how teams like the Rays and Royals will manage pitchers Drew Rasmussen and Kris Bubic, both returning from Tommy John surgery. Rasmussen pitched 36 innings last year as a reliever, while Bubic made 66 relief innings after minor league rehab starts. Their limited innings suggest caution for fantasy managers, as workload restrictions may reduce their value during the season’s latter stages. However, Rasmussen could potentially become the Rays’ closer later this year if Pete Fairbanks is traded.
Emerging Talents and Prospects Impacting Rankings
Marcelo Mayer makes a significant debut, entering the rankings at No. 209 after replacing the injured Alex Bregman at third base for Boston. While Mayer is not expected to excel in any single category, his role as a regular hitter in the middle of the Red Sox lineup provides a balanced contribution that fantasy owners can utilize. Bregman’s expected return after the midseason break may affect Mayer’s status moving forward.
Jac Caglianone, despite not receiving a major league callup recently, appears at No. 266 following an impressive five-homer stretch in four Triple-A games. Though a natural first baseman, Caglianone has seen outfield action as the Royals face roster holes in both left and right fields. Nick Loftin and John Rave, other Royals recent additions, have had mixed usage; Loftin started twice in five games post-recall, while Rave has appeared regularly yet may be platooned against left-handed pitchers.
Implications for Fantasy Managers as Season Progresses
The evolving roster changes and injury management strategies of MLB teams will continue to impact fantasy baseball dynamics. Monitor transactional moves like a possible trade involving Pete Fairbanks or the timing of returning players like Bregman closely. Such developments could trigger significant ranking adjustments and affect player values in rest-of-season projections.
Maintaining awareness of emerging prospects including Mayer and Caglianone could offer fantasy owners potential advantages, especially if injuries persist or regular starters underperform. The competition between ace sluggers Aaron Judge, Shohei Ohtani, and Bobby Witt Jr. sets a high standard at the top of the rankings, shaping the strategic approaches managers must consider throughout the remainder of the 2025 season.