Derrick Lewis, known for his formidable punching power, has delivered numerous knockouts throughout his UFC career, but one stands out above the rest. On February 20, 2021, inside the UFC Apex in Las Vegas, Nevada, Lewis faced Curtis Blaydes in a highly anticipated bout. The encounter ended dramatically when Lewis landed a devastating uppercut that knocked Blaydes unconscious, marking one of the most memorable moments of his career. This knockout remains especially meaningful due to the intense rivalry and frequent trash talk between the two fighters.

Lewis reflected on their dynamic in an interview with MMA Fighting, saying,

“The most satisfying was Curtis Blaydes. I was trying to be cool to that guy, speaking to him at events, and he never wanted to speak to me.”

He added,

Then, he started calling me out every chance he got, even after I fight, he’d call me out and talk trash.

—Derrick Lewis, UFC Heavyweight

Lewis Showcases Knockout Power Against Rodrigo Nascimento

Besides his victory over Blaydes, Lewis has continued to demonstrate his knockout ability. On May 11, 2024, at the Enterprise Center in St. Louis, Missouri, Lewis faced Rodrigo Nascimento in a striking display of strength. The American heavyweight unleashed a powerful strike that abruptly ended the fight, thrilling the crowd and reaffirming his status as one of the most feared finishers in the UFC.

Derrick Lewis’ Reputation for Devastating Knockouts

Lewis has earned a reputation as a fierce knockout artist within the sport, often intimidating opponents even before fights begin. UFC President Dana White has remarked that Lewis’ intensity during pre-fight staredowns is enough to unsettle him, underscoring the heavy psychological edge Lewis carries into the octagon. When the heavyweight steps inside the cage, his relentless punching power tends to seal the outcome, often in spectacular fashion.

The Impact of Lewis’ Knockout Highlights on His Career

Lewis’ knockout wins, particularly the one against Curtis Blaydes, have solidified his legacy as a heavyweight known not only for strength but also for resilience amid fierce rivalries. His ability to finish fights decisively maintains his popularity among fans and keeps him relevant in the competitive UFC landscape. Looking ahead, his track record suggests he will continue to be a dominant force capable of thrilling knockouts, shaping future matchups and rivalries.