Evaluating strikeout predictions is a crucial strategy when placing prop bets on MLB pitchers, and June 15, 2025, offers several intriguing matchups. With over/under strikeout lines set for many starters, bettors have notable opportunities to leverage insights on some of the game’s best pitchers.
This analysis focuses on five significant over/under strikeout prop bets, highlighting key pitchers starting on this day and their expected performance based on recent form and opposing lineups.
Max Fried Likely to Strike Out Fewer Than 7 Batters
Max Fried, who has been a standout for the New York Yankees in the 2025 season, faces a challenging matchup against the Boston Red Sox. While Fried is expected to deliver a strong performance on the mound, his strikeout total is projected to stay below 6.5 for this game. This makes the under 6.5 strikeouts bet (-140) the favored choice for bettors focusing on Fried’s output.
Zack Wheeler Expected to Achieve More Than 6.5 Strikeouts
Zack Wheeler consistently demonstrates dominance whenever he pitches, and his ability to overpower hitters places him in a strong position against the Toronto Blue Jays. Considering the Blue Jays’ high strikeout rate, taking the over 6.5 strikeouts (+105) on Wheeler appears to be a smart wager for June 15.
Nick Pivetta Poised to Exceed 4.5 Strikeouts
San Diego Padres pitcher Nick Pivetta, who currently boasts a 6-2 record with a 3.48 ERA this season, will start against the Arizona Diamondbacks. Although the matchup presents some difficulties, Pivetta is projected to record more than 4.5 strikeouts (-150), making the over bet an appealing option.
Reliable Choice: Colin Rea Over 4.5 Strikeouts
Among the safest selections for June 15 is Colin Rea of the Chicago Cubs, who is expected to strike out at least five batters in his game against the Pittsburgh Pirates. Rea’s performance should help secure a decisive win for the Cubs, reinforcing the over 4.5 strikeouts (-115) as a dependable pick.
Bold Strikeout Prediction Featuring Miles Mikolas
For those seeking a bold prop bet, Miles Mikolas is one to watch in his outing versus the Milwaukee Brewers. Despite not being known for a high strikeout rate, Mikolas is anticipated to reach at least four strikeouts, making the over 3.5 strikeouts (+115) a bold but reasonable selection.
Impact and What to Watch Next
These strikeout prop bets offer bettors strategic plays based on pitcher matchups, recent performances, and opposing team tendencies. Max Fried’s under 6.5 strikeouts prediction stands out as a well-founded choice given his matchup challenges, while other pitchers like Zack Wheeler and Colin Rea present compelling over bets. Observing how these predictions unfold could influence future betting strategies as the 2025 MLB season progresses.