Betting on Riley Greene MLB home run props has gained notable attention for Monday, Aug. 18, as several promising matchups highlight the slate. Detroit Tigers outfielder Riley Greene, Los Angeles Dodgers’ Shohei Ohtani, and Cleveland Guardians’ Kyle Manzardo stand out as players with favorable conditions to hit home runs, making them attractive choices for bettors looking to capitalize on plus odds. These selections come amid pitching struggles faced by their respective opponents on the day.

The focus is on exploiting weaknesses in the pitching matchups and leveraging players’ past performances against these pitchers, bringing a hopeful outlook to prop betting markets on this Major League Baseball slate.

Riley Greene’s Advantage Against Houston’s Spencer Arrighetti

Though Riley Greene has experienced a batting slump since the All-Star break, hitting just .204 in his last 24 games, the matchup on Monday suggests a bounce-back opportunity. Greene will face Houston Astros’ Spencer Arrighetti, who currently holds a 6.38 ERA and has conceded two home runs in four appearances this season.

Historically, Greene has excelled against Arrighetti, recording two home runs and four RBIs in two career at-bats, demonstrating exceptional success specific to this pitcher. Given that Greene has hit .289 overall with 26 of his 28 home runs this season against right-handed pitchers like Arrighetti, his home run prop at +425 odds emerges as a compelling wager for bettors.

Shohei Ohtani’s Strong Track Record Against Rockies’ Kyle Freeland

Shohei Ohtani, a key figure for the Los Angeles Dodgers, has homered 43 times during the 2025 season, making him one of the most reliable home run bet candidates on this Monday’s lineup. Ohtani will bat against Colorado Rockies left-hander Kyle Freeland, who has struggled this season with a 5.18 ERA and has allowed 16 home runs across 22 starts.

Ohtani’s career numbers versus Freeland support this selection, with a 4-for-6 hitting record including two home runs and a double, resulting in an OPS of 2.500. In addition, Ohtani has hit better against left-handed pitchers this season, batting .283 with 10 home runs and an OPS close to .900, reinforcing his value as a home run prop pick at +160 odds.

Kyle Manzardo’s Opportunity Against Diamondbacks Starter Zac Gallen

The Cleveland Guardians continue to push for playoff contention, and Kyle Manzardo’s matchup against Arizona Diamondbacks starter Zac Gallen looks promising for home run prop bettors. Gallen has allowed 24 home runs in 25 starts this year and posted a 5.31 ERA, marking him as a vulnerable pitcher in terms of long balls allowed.

Manzardo, a left-handed slugger with 21 home runs this season (17 against right-handed pitching), is coming off a strong recent stretch. He has hit three home runs across his last 10 games while maintaining a .276 batting average and a 1.057 OPS during that span. With odds at +380, Manzardo represents a well-supported choice for hitting a home run on Monday night.

Implications for Bettors and What to Expect Moving Forward

Monday’s home run prop bets featuring Riley Greene, Shohei Ohtani, and Kyle Manzardo highlight the importance of analyzing pitching matchups and player histories when placing wagers. Greene’s success against Arrighetti, combined with Ohtani’s dominance over Freeland and Manzardo’s recent hot streak against Gallen, illustrates how strategic prop betting can capitalize on favorable odds.

As the season progresses, attention to such detailed pitching vs. batter scenarios will remain critical. Bettors looking to find value in MLB home run props should continue monitoring pitcher vulnerabilities, batting splits, and historical performance to increase their chances of cashing in on these markets.

Odds are subject to change throughout the day, and responsible gambling resources are available for those seeking help with wagering challenges.